interfete_biohibride

Realizarea de interfete biohibride siliciu-proteine cu aplicatii in bionanodetectie

Rezultate

Raport de faza 2008 [...]

Publicatii

CAS 2008 Proceedings
Preparation of SERS-active porous gold substrate, Teodora Ignat, Irina Kleps, Mihaela Miu, Florin Craciunoiu, Adina Bragaru, Monica Simion,� CAS 2008 Proceedings, pg. 197-200
Superlattices and Microstructures
Porous Silicon Used As Support for Protein Microarray, M. Simion, L. Ruta, C. Mihilescu, I. Kleps, A. Bragaru, M. Miu, T. Ignat, Ion Baciu, Superlattices and Microstructures, doi:10.1016/j.spmi.2008.11.024, online 10 January 2009
Journal of Biomedical Nanotechnology (JBN)
Study of the Micro- and Nanostructured Silicon for Biosensing and Medical Applications
Irina Kleps, Mihaela Miu, Monica Simion, Teodora Ignat, Adina Bragaru, Florea Craciunoiu, and Mihai Danila, Journal of Biomedical Nanotechnology, Vol.5, 1�10, 2009
Journal of Nanoscience and Nanotechnology (JNN)
Nanostructured Silicon Particles for Medical Applications, Irina Kleps, Teodora Ignat, Mihaela Miu, Florea Craciunoiu, Mihaela Trif, Monica Simion, Adina Bragaru, and Adrian Dinescu, Journal of Nanoscience and Nanotechnology Vol.9, 1�7, 2009.
Physica Status Solodi C (PSSC)
Protein-mesoporous silicon matrix obtained by S-layer technology, Irina Kleps, Teodora Ignat, Mihaela Miu, Monica Simion, Gabriela Teodosiu Popescu, Madalin Enache, Lucia Dumitru, Physica Status Solodi C (PSSC), no. 7, 1605-1609, 2009.
Acceptata pentru publicare in Superlattices and Microstructures:
Nanostructured Au/Si substrate for organic molecule SERS detection, Teodora Ignat, Irina Kleps, Mihaela Miu, Adina Bragaru, Monica Simion, Superlattices and Microstructures, 2009.
Acceptata pentru publicare:
216th ECS Meeting Proceeding (2009):
Metal � Semiconductor Nanoassemblies for Improving of Sensing Efficiency
M. Miu, I. Kleps, M.Danila, T. Ignat, M. Simion, and A. Bragaru
Volumul, Micro-Nanongineering, editura Academiei Romane
Gold Nanoparticles for SEIRS, Teodora IGNAT, Fouad MAROUN, Phillippe ALLONGUE, NEW APPLICATIONS OF MICROAND NANOTECHNOLOGIES, Volumul Micro-Nanoengineering, EDITURA ACADEMIEI ROM�N, Bucure�ti, 2009, pp. 220-228.

Comunicari:

INOR- 6th International Conference on Inorganic Materials- Sesiunea Nanostructured and hybrid materials 2008, Study of the Au/ Porous Silicon substrate for Organic Molecules Biosensing, Irina Kleps, Mihaela Miu, Monica Simion, Teodora Ignat, Adina Bragaru.
216th ECS Meeting in Vienna, Austria (oct. 2009):
Abstract Number/Title: # 3150: Electrochemical Investigation of Porous Silicon/Gold System in Biological Electrolyte by M. Simion, I. Kleps, M. Miu, M. Danila and A. Bragaru
Seminarul National de Nanostiinta si Nanotehnologii (Academia Romana) (martie 2009)
"Filme organice subtiri cu aplicatii in biomedicina", T.Ignat, I.Kleps, A. Bragaru, M.Simion, M.Miu, F. Craciunoiu
"Porous Silicon Layer For Protein Immobilization", M. Simion, M. Miu, I. Kleps, A. Bragaru, T. Ignat, L. Ruta, I. Baciu, C. Mihailescu, D. Stan

CERERE DE BREVET DE INVENTIE: in curs de elaborare

Titlu: Realizarea unei platforme pe un chip de Si de testare a interfetelor biohibride, cu care sa se poata efectua masuratori electrice si optice;
Autori: Irina Kleps, Mihaela Miu, Teodora Ignat, Monica Simion, Adina Bragaru

*****************

Obiectivele propuse, studiul interfetelor biohibride (Si-proteine) si detectia unui semnal IR si/sau Raman amplificat datorat nanostructurarii suprafetei, precum si formarea unor legaturi stabile biomolecula-suprafata dispozitiv sunt urmarite cu scopul dezvoltarii a doua aplicatii specifice in lucru in laborator si anume biosenzor cu detectie optica si biochip cu proteine pentru diagnosticare medicala.

Potentiali utilizatori

Proiectul propus este in concordanta cu obiectivele strategice ale sistemului national CDI contribuind la crearea de cunoastere in domenii multidisciplinare (biofizica, stiinta suprafetelor, nanotehnologii, bionanomateriale), cu impact in diferite sectoare: (nano)medicina, mediu (toxicologie), alimentar, in bio(nano)detectie si proteomica. Cunostintele acumulate in proiect vor contribui la crearea de (bio)nanomateriale, dispozitive si tehnologii inovative.

	Realizarea de interfete biohibride siliciu-proteine cu aplicatii in bionanodetectie
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	Rezultate Raport de faza 2008 [...] Publicatii *CAS 2008 Proceedings* Preparation of SERS-active porous gold substrate, Teodora Ignat, Irina Kleps, Mihaela Miu, Florin Craciunoiu, Adina Bragaru, Monica Simion,� CAS 2008 Proceedings, pg. 197-200 *Superlattices and Microstructures* Porous Silicon Used As Support for Protein Microarray, M. Simion, L. Ruta, C. Mihilescu, I. Kleps, A. Bragaru, M. Miu, T. Ignat, Ion Baciu, Superlattices and Microstructures, doi:10.1016/j.spmi.2008.11.024, online 10 January 2009 *Journal of Biomedical Nanotechnology (JBN)* Study of the Micro- and Nanostructured Silicon for Biosensing and Medical Applications Irina Kleps, Mihaela Miu, Monica Simion, Teodora Ignat, Adina Bragaru, Florea Craciunoiu, and Mihai Danila, Journal of Biomedical Nanotechnology, Vol.5, 1�10, 2009 *Journal of Nanoscience and Nanotechnology (JNN)* Nanostructured Silicon Particles for Medical Applications, Irina Kleps, Teodora Ignat, Mihaela Miu, Florea Craciunoiu, Mihaela Trif, Monica Simion, Adina Bragaru, and Adrian Dinescu, Journal of Nanoscience and Nanotechnology Vol.9, 1�7, 2009. *Physica Status Solodi C (PSSC)* Protein-mesoporous silicon matrix obtained by S-layer technology, Irina Kleps, Teodora Ignat, Mihaela Miu, Monica Simion, Gabriela Teodosiu Popescu, Madalin Enache, Lucia Dumitru, Physica Status Solodi C (PSSC), no. 7, 1605-1609, 2009. *Acceptata pentru publicare in Superlattices and Microstructures:* Nanostructured Au/Si substrate for organic molecule SERS detection, Teodora Ignat, Irina Kleps, Mihaela Miu, Adina Bragaru, Monica Simion, Superlattices and Microstructures, 2009. *Acceptata pentru publicare:* 216th ECS Meeting Proceeding (2009): Metal � Semiconductor Nanoassemblies for Improving of Sensing Efficiency M. Miu, I. Kleps, M.Danila, T. Ignat, M. Simion, and A. Bragaru *Volumul, Micro-Nanongineering, editura Academiei Romane* Gold Nanoparticles for SEIRS, Teodora IGNAT, Fouad MAROUN, Phillippe ALLONGUE, NEW APPLICATIONS OF MICROAND NANOTECHNOLOGIES, Volumul Micro-Nanoengineering, EDITURA ACADEMIEI ROM�N, Bucure�ti, 2009, pp. 220-228. Comunicari: INOR- 6th International Conference on Inorganic Materials- Sesiunea Nanostructured and hybrid materials 2008, Study of the Au/ Porous Silicon substrate for Organic Molecules Biosensing, Irina Kleps, Mihaela Miu, Monica Simion, Teodora Ignat, Adina Bragaru. 216th ECS Meeting in Vienna, Austria (oct. 2009): Abstract Number/Title: # 3150: Electrochemical Investigation of Porous Silicon/Gold System in Biological Electrolyte by M. Simion, I. Kleps, M. Miu, M. Danila and A. Bragaru Seminarul National de Nanostiinta si Nanotehnologii (Academia Romana) (martie 2009) "Filme organice subtiri cu aplicatii in biomedicina", T.Ignat, I.Kleps, A. Bragaru, M.Simion, M.Miu, F. Craciunoiu "Porous Silicon Layer For Protein Immobilization", M. Simion, M. Miu, I. Kleps, A. Bragaru, T. Ignat, L. Ruta, I. Baciu, C. Mihailescu, D. Stan CERERE DE BREVET DE INVENTIE: in curs de elaborare *Titlu:* Realizarea unei platforme pe un chip de Si de testare a interfetelor biohibride, cu care sa se poata efectua masuratori electrice si optice; *Autori:* Irina Kleps, Mihaela Miu, Teodora Ignat, Monica Simion, Adina Bragaru *************** Obiectivele propuse, studiul interfetelor biohibride (Si-proteine) si detectia unui semnal IR si/sau Raman amplificat datorat nanostructurarii suprafetei, precum si formarea unor legaturi stabile biomolecula-suprafata dispozitiv sunt urmarite cu scopul dezvoltarii a doua aplicatii specifice in lucru in laborator si anume biosenzor cu detectie optica si biochip cu proteine pentru diagnosticare medicala. Potentiali utilizatori** Proiectul propus este in concordanta cu obiectivele strategice ale sistemului national CDI contribuind la crearea de cunoastere in domenii multidisciplinare (biofizica, stiinta suprafetelor, nanotehnologii, bionanomateriale), cu impact in diferite sectoare: (nano)medicina, mediu (toxicologie), alimentar, in bio(nano)detectie si proteomica. Cunostintele acumulate in proiect vor contribui la crearea de (bio)nanomateriale, dispozitive si tehnologii inovative.