Objectives
The objective of the complex project is to develop new diagnostic methods for monitoring the pregnant woman and the foetus with the purpose to avoid life-threatening complications by making biomedical devices associated with use protocols.
The Complex Project „New methods of pregnancy monitoring and prenatal diagnosis” proposes to define and develop new biomedical devices for pregnant women and foetus monitoring, with the purpose to avoid life-threatening complications for both, the mother and the child. It will be developed through four Component Projects as follows:
1. Prenatal non-invasive screening, using cell free fetal DNA, extracted from the mother’s blood. It will develop a chip for the non-invasive detection of the SRY gene, together with a working protocol for a new type of non-invasive analysis for the early prenatal diagnosis.
2. Non-invasive microsensors for continuous glucose monitoring during pregnancy – proposes the technology development for a non-invasive glucose sensor to measure the glucose level in saliva. The project will support the continuous monitoring of pregnant women, avoiding dangers effects coming from the invasive methods (inflammations, infections).
3. Evaluation of premature birth risks due to the HPV-EVA-RINA infection. The project will develop clinical studies related to the HPC infection involvement in triggering premature birth, using genotyping microarray-type structures;
4. Wireless multi-sensor system for foetal activity and uterine contractions monitoring and classification during pregnancy – aims to develop an intelligent system, containing a wireless network of wearable sensors and a main unit for signal processing and analysis.
The complex project description includes the novelty elements, detailed activities description, the working procedures within the consortium, expected results and deliverables. The deliverables has an average TRL 5, which means all four component projects will have a high technological level and the result’s maturity will reach at least successful laboratory testing.
|
